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Anti-BAI2 Antibody

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产品名称: Anti-BAI2 Antibody
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简单介绍

Anti-BAI2 Antibody


Anti-BAI2 Antibody  的详细介绍
Name: Anti-BAI2 Antibody
See all BAI2 primary antibodies
Description: Rabbit polyclonal antibody to BAI2
Specificity: The antibody detects endogenous levels of total BAI2 protein.
Applications: IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to residues near the C terminal of human brain-specific angiogenesis inhibitor 2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.9mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Orphan receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT signaling pathway probably via a G-protein dependent pathway (PubMed:20367554). Might be involved in angiogenesis inhibition (By similarity).
Tissue Specificity: Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines.
Sequence Similarities: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Post-Translational Modification: Proteolytically cleaved at 2 conserved sites: one in the GPS domain (S1 site) and the other in the middle of the extracellular domain (S2 site). The proteolytic cleavage at S1 site generates an extracellular subunit and a seven-transmembrane subunit. Furin is involved in the cleavage of the S2 site generating a soluble fragment.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 576?Human
  • Entrez Gene: 230775?Mouse
  • Omim: 602683?Human
  • SwissProt: O60241?Human
  • SwissProt: Q8CGM1?Mouse
  • Unigene: 200586?Human
  • Unigene: 262241?Mouse
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    Synonyms:
  • BAI2 Antibody
  • Brain Specific Angiogenesis Inhibitor 2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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