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Anti-ATP6AP2 Antibody

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产品名称: Anti-ATP6AP2 Antibody
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Anti-ATP6AP2 Antibody


Anti-ATP6AP2 Antibody  的详细介绍
Name: Anti-ATP6AP2 Antibody
See all ATP6AP2 primary antibodies
Description: Rabbit polyclonal antibody to ATP6AP2.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity: Human
Immunogen: Recombinant protein of human ATP6AP2.
Protein Length: 350
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).
Tissue Specificity: Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.
Involvement in Disease: Mental retardation, X-linked, with epilepsy: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRXE patients manifest mild to moderate mental retardation associated with epilepsy, delays in motor milestones and speech acquisition in infancy.

Parkinsonism with spasticity, X-linked: A syndrome characterized by parkinsonian features, such as cogwheel rigidity, resting tremor and bradykinesia, and variably penetrant spasticity.
Post-Translational Modification: Phosphorylated.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 10159?Human
  • Omim: 300556?Human
  • SwissProt: O75787?Human
  • Unigene: 495960?Human
    		•
    Synonyms:
  • APT6M8 9 Antibody
  • APT6M8-9 Antibody
  • ATP6AP2 Antibody
  • ATP6IP2 Antibody
  • ATP6M8-9 Antibody
  • ATPase H(+)-transporting lysosomal accessory protein 2 Antibody
  • ATPase H(+)-transporting lysosomal-interacting protein 2 Antibody
  • ATPase H+ transporting lysosomal accessory protein 2 Antibody
  • ATPase H+ transporting lysosomal interacting protein 2 Antibody
  • ATPase H+ transporting lysosomal vacuolar proton pump membrane sector associated protein M8 9 Antibody
  • ATPase membrane sector associated protein M8 9 Antibody
  • ATPase, H+ transporting, lysosomal (vacuolar proton pump) membrane sector associated protein M8 9 Antibody
  • CAPER Antibody
  • ELDF10 Antibody
  • Embryonic liver differentiation factor 10 Antibody
  • ER localized type I transmembrane adaptor Antibody
  • ER-localized type I transmembrane adaptor Antibody
  • HT028 Antibody
  • M8 9 Antibody
  • M8-9 Antibody
  • MGC99577 Antibody
  • MRXE Antibody
  • MSTP009 Antibody
  • N14F Antibody
  • Renin receptor Antibody
  • Renin/prorenin receptor Antibody
  • RENR_HUMAN Antibody
  • V ATPase M8 9 subunit Antibody
  • V ATPase M8.9 subunit Antibody
  • V-ATPase M8.9 subunit Antibody
  • Vacuolar ATP synthase membrane sector associated protein M8 9 Antibody
  • Vacuolar ATP synthase membrane sector-associated protein M8-9 Antibody
  • vacuolar proton ATP synthase membrane sector associated protein M8 9 Antibody
  • XMRE Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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