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Anti-ATIC Antibody

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产品名称: Anti-ATIC Antibody
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简单介绍

Anti-ATIC Antibody


Anti-ATIC Antibody  的详细介绍
Name: Anti-ATIC Antibody
See all ATIC primary antibodies
Description: Rabbit polyclonal antibody to ATIC
Specificity: The antibody detects endogenous levels of total ATIC protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein of human ATIC
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis.
Involvement in Disease: AICAR transformylase/IMP cyclohydrolase deficiency: A neurologically devastating inborn error of purine biosynthesis. Patients excrete massive amounts of AICA-riboside in the urine and accumulate AICA-ribotide and its derivatives in erythrocytes and fibroblasts. AICAR causes profound mental retardation, epilepsy, dysmorphic features and congenital blindness.
Sequence Similarities: Belongs to the PurH family.
Database Links:
  • Entrez Gene: 471?Human
  • Omim: 601731?Human
  • SwissProt: P31939?Human
  • Unigene: 90280?Human
    		•
    Synonyms:
  • AICAR formyltransferase/IMP cyclohydrolase Antibody
  • 5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase Antibody
  • 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase Antibody
  • 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Antibody
  • 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase Antibody
  • AICAR Antibody
  • AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme Antibody
  • AICAR transformylase Antibody
  • AICARFT Antibody
  • AICARFT/IMPCHASE Antibody
  • ATIC Antibody
  • Bifunctional purine biosynthesis protein PURH Antibody
  • epididymis secretory sperm binding protein Li 70p Antibody
  • FLJ93545 Antibody
  • HEL-S-70p Antibody
  • IMP cyclohydrolase Antibody
  • IMP synthase Antibody
  • IMP synthetase Antibody
  • IMPCHASE Antibody
  • Inosinicase Antibody
  • OK/SW-cl.86 Antibody
  • Phosphoribosylaminoimidazolecarboxamide formyltransferase Antibody
  • Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Antibody
  • PUR9_HUMAN Antibody
  • PURH Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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