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Anti-ATG4B Antibody

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产品名称: Anti-ATG4B Antibody
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简单介绍

Anti-ATG4B Antibody


Anti-ATG4B Antibody  的详细介绍
Name: Anti-ATG4B Antibody
See all ATG4B primary antibodies
Description: Rabbit polyclonal antibody to ATG4B
Specificity: The antibody detects endogenous levels of total ATG4B protein.
Applications: IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human autophagy related 4B, cysteine peptidase
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Tissue Specificity: Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas.
Sequence Similarities: Belongs to the peptidase C54 family.
Cellular Location: Cytoplasm.
Database Links:
  • Entrez Gene: 23192?Human
  • Omim: 611338?Human
  • SwissProt: Q9Y4P1?Human
  • Unigene: 283610?Human
    		•
    Synonyms:
  • APG4 autophagy 4 homolog B Antibody
  • APG4B Antibody
  • ATG4 autophagy related 4 homolog B (S. cerevisiae) Antibody
  • ATG4B Antibody
  • ATG4B_HUMAN Antibody
  • AUT like 1 cysteine endopeptidase Antibody
  • AUT-like 1 cysteine endopeptidase Antibody
  • AUTL1 Antibody
  • Autophagin 1 Antibody
  • Autophagin-1 Antibody
  • Autophagy related 4B cysteine peptidase Antibody
  • Autophagy related cysteine endopeptidase 1 Antibody
  • Autophagy related protein 4 homolog B Antibody
  • Autophagy-related cysteine endopeptidase 1 Antibody
  • Autophagy-related protein 4 homolog B Antibody
  • Cysteine protease ATG4B Antibody
  • hAPG4B Antibody
  • MGC1353 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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