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Anti-PNPLA8 Antibody

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产品名称: Anti-PNPLA8 Antibody
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简单介绍

Anti-PNPLA8 Antibody


Anti-PNPLA8 Antibody  的详细介绍
Name: Anti-PNPLA8 Antibody
See all PNPLA8 primary antibodies
Description: Rabbit polyclonal antibody to PNPLA8
Specificity: The antibody detects endogenous levels of total PNPLA8 protein.
Applications: WB
Reactivity: Human, Mouse
Immunogen: Synthesized peptide derived from internal of human PNPLA8.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids.
Tissue Specificity: Expressed in parenchymal tissues including heart, skeletal muscle, placenta, brain, liver and pancreas. Also expressed in bronchial epithelial cells and kidney. Highest expression is observed in skeletal muscle and heart.
Involvement in Disease: Mitochondrial myopathy with lactic acidosis: An autosomal recessive disorder characterized by progressive muscle weakness, hypotonia, seizures, poor weight gain, lactic acidosis, and elevated serum pyruvate concentration. Some patients manifest growth failure and moderate neural deafness.
Cellular Location: Endoplasmic reticulum membrane. Golgi apparatus membrane. Cytoplasm > Perinuclear region.
Database Links:
  • Entrez Gene: 50640 Human
  • Entrez Gene: 67452 Mouse
  • Omim: 612123 Human
  • SwissProt: Q9NP80 Human
  • SwissProt: Q8K1N1 Mouse
  • Unigene: 617340 Human
  • Unigene: 732217 Human
  • Unigene: 54126 Mouse
    		•
    Synonyms:
  • Calcium-independent phospholipase A2-gamma Antibody
  • Intracellular membrane associated calcium independent phospholipase A2 gamma Antibody
  • Intracellular membrane-associated calcium-independent phospholipase A2 gamma Antibody
  • IPLA2 2 Antibody
  • iPLA2 gamma Antibody
  • IPLA2(GAMMA) Antibody
  • iPLA2-2 Antibody
  • iPLA2-gamma Antibody
  • IPLA22 Antibody
  • IPLA2G Antibody
  • Patatin like phospholipase domain containing protein 8 Antibody
  • Patatin-like phospholipase domain-containing protein 8 Antibody
  • PLPL8_HUMAN Antibody
  • PNPLA-gamma Antibody
  • PNPLA8 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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