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Anti-SMEK1 Antibody

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产品名称: Anti-SMEK1 Antibody
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简单介绍

Anti-SMEK1 Antibody


Anti-SMEK1 Antibody  的详细介绍
Name: Anti-SMEK1 Antibody
See all SMEK1 primary antibodies
Description: Rabbit polyclonal antibody to SMEK1.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant Protein of human SMEK1.
Protein Length: 833 (594)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Sequence Similarities: Belongs to the SMEK family.
Cellular Location: Cytoplasm. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome. Nucleus.

In interphase localized in the cytoplasm and in the nucleus (with higher levels). During metaphase located in pericentriolar regions.
Database Links:
  • Entrez Gene: 55671?Human
  • Entrez Gene: 68734?Mouse
  • Entrez Gene: 314388?Rat
  • Omim: 610351?Human
  • SwissProt: Q6IN85?Human
  • SwissProt: Q6P2K6?Mouse
  • Unigene: 533887?Human
  • Unigene: 87077?Mouse
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    Synonyms:
  • FLFL1 Antibody
  • KIAA2010 Antibody
  • MEK1 SUPPRESSOR 1 Antibody
  • MSTP033 Antibody
  • P4R3A_HUMAN Antibody
  • PP4R3 Antibody
  • PP4R3 ALPHA Antibody
  • PP4R3A Antibody
  • PPP4R3A Antibody
  • Protein phosphatase 4 regulatory subunit 3A Antibody
  • PROTEIN PHOSPHATASE 4, REGULATORY SUBUNIT 3, ALPHA Antibody
  • Serine/threonine-protein phosphatase 4 regulatory subunit 3A Antibody
  • SMEK homolog 1 Antibody
  • SMEK homolog 1, suppressor of mek1 (Dictyostelium) Antibody
  • Smek1 Antibody
  • Smk 1 Antibody
  • SMK1 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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