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Anti-SLC25A13 Antibody

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产品名称: Anti-SLC25A13 Antibody
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Anti-SLC25A13 Antibody


Anti-SLC25A13 Antibody  的详细介绍
Name: Anti-SLC25A13 Antibody
See all SLC25A13 primary antibodies
Description: Rabbit polyclonal antibody to SLC25A13
Specificity: The antibody detects endogenous levels of total SLC25A13 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein of human SLC25A13
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.1mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.
Tissue Specificity: High levels in liver and low levels in kidney, pancreas, placenta, heart and brain.
Involvement in Disease: Citrullinemia 2: A form of citrullinemia, an autosomal recessive disease characterized primarily by elevated serum and urine citrulline levels. Ammonia intoxication is another manifestation. Citrullinemia type 2 is characterized by neuropsychiatric symptoms including abnormal behaviors, loss of memory, seizures and coma. Death can result from brain edema. Onset is sudden and usually between the ages of 20 and 50 years.

Cholestasis, neonatal intrahepatic, caused by citrin deficiency: A form of citrullinemia type 2 with neonatal onset, characterized by suppression of the bile flow, hepatic fibrosis, low birth weight, growth retardation, hypoproteinemia, variable liver dysfunction. Neonatal intrahepatic cholestasis due to citrin deficiency is generally not severe and symptoms disappear by one year of age with an appropriate diet. Years or even decades later, however, some individuals develop the characteristic features of citrullinemia type 2 with neuropsychiatric symptoms.
Sequence Similarities: Belongs to the mitochondrial carrier (TC 2.A.29) family.
Cellular Location: Mitochondrion inner membrane.
Database Links:
  • Entrez Gene: 10165?Human
  • Omim: 603859?Human
  • SwissProt: Q9UJS0?Human
  • Unigene: 489190?Human
    		•
    Synonyms:
  • AI785475 Antibody
  • ARALAR2 Antibody
  • Calcium binding mitochondrial carrier protein Aralar2 Antibody
  • Calcium-binding mitochondrial carrier protein Aralar2 Antibody
  • Citrin Antibody
  • CMC2_HUMAN Antibody
  • CTLN2 Antibody
  • Ctrn Antibody
  • Mitochondrial aspartate glutamate carrier 2 Antibody
  • RGD1565889 Antibody
  • SLC25A13 Antibody
  • Solute carrier family 25 (citrin) member 13 Antibody
  • Solute carrier family 25 member 13 Antibody
  • Solute carrier family 25 member 13 (citrin) Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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