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Anti-SLC24A6 Antibody

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产品名称: Anti-SLC24A6 Antibody
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简单介绍

Anti-SLC24A6 Antibody


Anti-SLC24A6 Antibody  的详细介绍
Name: Anti-SLC24A6 Antibody
See all SLC24A6 primary antibodies
Description: Rabbit polyclonal antibody to SLC24A6
Specificity: The antibody detects endogenous levels of total SLC24A6 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 8 (sodium / lithium / calcium exchanger), member B1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, thereby acting as a key regulator of mitochondrion calcium homeostasis. Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses. Able to transport Ca(2+) in exchange of either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+).
Tissue Specificity: Present in pancreatic beta-cells (at protein level).
Sequence Similarities: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
Cellular Location: Mitochondrion inner membrane.
Database Links:
  • Entrez Gene: 80024?Human
  • Omim: 609841?Human
  • SwissProt: Q6J4K2?Human
  • Unigene: 286194?Human
    		•
    Synonyms:
  • FLJ22233 Antibody
  • Na(+)/K(+)/Ca(2+) exchange protein 6 Antibody
  • Na(+)/K(+)/Ca(2+)-exchange protein 6 Antibody
  • NCKX6 Antibody
  • NCKX6_HUMAN Antibody
  • NCLX Antibody
  • SLC24A6 Antibody
  • Sodium/potassium/calcium exchanger Antibody
  • Sodium/potassium/calcium exchanger 6 Antibody
  • Solute carrier family 24 (sodium/potassium/calcium exchanger) member 6 Antibody
  • Solute carrier family 24 member 6 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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