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Anti-SIRT3 Antibody

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产品名称: Anti-SIRT3 Antibody
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简单介绍

Anti-SIRT3 Antibody


Anti-SIRT3 Antibody  的详细介绍
Name: Anti-SIRT3 Antibody
See all SIRT3 primary antibodies
Description: Rabbit polyclonal antibody to SIRT3.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100, IF: 1:50 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic peptide of human SIRT3.
Protein Length: 399
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: NAD-dependent protein deacetylase. Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues. Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA and the ATP synthase subunit ATP5O. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Tissue Specificity: Widely expressed.
Sequence Similarities: Belongs to the sirtuin family. Class I subfamily.
Post-Translational Modification: Processed by mitochondrial processing peptidase (MPP) to give a 28 kDa product. Such processing is probably essential for its enzymatic activity.
Cellular Location: Mitochondrion matrix.
Database Links:
  • Entrez Gene: 23410?Human
  • Entrez Gene: 64384?Mouse
  • Entrez Gene: 293615?Rat
  • Omim: 604481?Human
  • SwissProt: Q9NTG7?Human
  • SwissProt: Q8R104?Mouse
  • Unigene: 716456?Human
  • Unigene: 244216?Mouse
  • Unigene: 24698?Rat
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    Synonyms:
  • hSIRT 3 Antibody
  • hSIRT3 Antibody
  • Mitochondrial nicotinamide adenine dinucleotide dependent deacetylase Antibody
  • NAD dependent deacetylase sirtuin 3 mitochondrial Antibody
  • NAD-dependent protein deacetylase sirtuin-3, mitochondrial Antibody
  • Regulatory protein SIR2 homolog 3 Antibody
  • Silent mating type information regulation 2 S.cerevisiae homolog 3 Antibody
  • Sir 2 like 3 Antibody
  • SIR 2 like protein 3 Antibody
  • SIR 3 Antibody
  • SIR2 L3 Antibody
  • Sir2 like 3 Antibody
  • SIR2 like protein 3 Antibody
  • SIR2-like protein 3 Antibody
  • SIR2L3 Antibody
  • SIR3_HUMAN Antibody
  • SIRT 3 Antibody
  • SIRT3 Antibody
  • Sirtuin 3 Antibody
  • Sirtuin silent mating type information regulation 2 homolog 3 (S. cerevisiae) Antibody
  • Sirtuin type 3 Antibody
  • Sirtuin3 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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