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Anti-SHMT2 Antibody

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产品名称: Anti-SHMT2 Antibody
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简单介绍

Anti-SHMT2 Antibody


Anti-SHMT2 Antibody  的详细介绍
Name: Anti-SHMT2 Antibody
See all SHMT2 primary antibodies
Description: Rabbit polyclonal antibody to SHMT2
Specificity: SHMT2 pAb detects endogenous levels of SHMT2 protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human SHMT2.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 56 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: Contributes to the de novo mitochondrial thymidylate biosynthesis pathway via its role in glycine and tetrahydrofolate metabolism. Thymidylate biosynthesis is required to prevent uracil accumulation in mtDNA (PubMed:21876188). Interconversion of serine and glycine (PubMed:25619277). Associates with mitochondrial DNA (PubMed:18063578). Plays a role in the deubiquitination of target proteins as component of the BRISC complex (PubMed:24075985). Required for IFNAR1 deubiquitination by the BRISC complex (PubMed:24075985).
Sequence Similarities: Belongs to the SHMT family.
Cellular Location: Mitochondrion. Mitochondrion matrix > Mitochondrion nucleoid. Mitochondrion inner membrane. Cytoplasm. Nucleus.
Database Links:
  • Entrez Gene: 6472?Human
  • Entrez Gene: 108037?Mouse
  • Entrez Gene: 299857?Rat
  • Omim: 138450?Human
  • SwissProt: P34897?Human
  • Unigene: 741179?Human
    		•
    Synonyms:
  • Epididymis secretory sperm binding protein Li 51e Antibody
  • GLY A+ Antibody
  • GLYA Antibody
  • glycine auxotroph A, human complement for hamster Antibody
  • Glycine hydroxymethyltransferase Antibody
  • GLYM_HUMAN Antibody
  • HEL S 51e Antibody
  • mitochondrial Antibody
  • Serine hydroxymethyltransferase Antibody
  • Serine hydroxymethyltransferase 2 (mitochondrial) Antibody
  • Serine hydroxymethyltransferase mitochondrial Antibody
  • Serine methylase Antibody
  • SHMT Antibody
  • SHMT 2 Antibody
  • SHMT2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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