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Anti-SGTA Antibody

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产品名称: Anti-SGTA Antibody
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简单介绍

Anti-SGTA Antibody


Anti-SGTA Antibody  的详细介绍
Name: Anti-SGTA Antibody
See all SGTA primary antibodies
Description: Rabbit polyclonal antibody to SGTA.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity: Human
Immunogen: Recombinant protein of human SGTA.
Protein Length: 313
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Co-chaperone involved in the regulation of the endoplasmic reticulum-associated misfolded protein catabolic process via its interaction with BAG6: collaborates with the BAG6 complex to maintain hydrophobic substrates in non-ubiquitinated states (PubMed:23129660, PubMed:25179605). Acts by competing with RNF126 for interacting the BAG6, preventing ubiquitination of BAG6 target proteins (PubMed:27193484). Binds directly to HSC70 and HSP70 and regulates their ATPase activity (PubMed:18759457).
Tissue Specificity: Ubiquitous.
Sequence Similarities: Belongs to the SGT family.
Cellular Location: Cytoplasm. Nucleus.

Co-localizes with HSP90AB1 in the cytoplasm. Increased nuclear accumulation seen during cell apoptosis.
Database Links:
  • Entrez Gene: 6449?Human
  • Omim: 603419?Human
  • SwissProt: O43765?Human
  • SwissProt: Q6FIA9?Human
  • Unigene: 203910?Human
    		•
    Synonyms:
  • Alpha SGT Antibody
  • Alpha-SGT Antibody
  • AlphaSGT Antibody
  • hSGT Antibody
  • SGT Antibody
  • Sgt1 Antibody
  • SGTA Antibody
  • SGTA_HUMAN Antibody
  • Small glutamine rich protein with tetratricopeptide repeats 1 Antibody
  • Small glutamine rich tetratricopeptide repeat containing protein alpha Antibody
  • Small glutamine rich tetratricopeptide repeat TPR containing alpha Antibody
  • Small glutamine rich tetratricopeptide repeat-containing protein Antibody
  • Small glutamine-rich tetratricopeptide repeat-containing protein alpha Antibody
  • Stg Antibody
  • UBP Antibody
  • Vpu binding protein Antibody
  • Vpu-binding protein Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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