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Anti-SGCE Antibody

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产品名称: Anti-SGCE Antibody
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简单介绍

Anti-SGCE Antibody


Anti-SGCE Antibody  的详细介绍
Name: Anti-SGCE Antibody
See all SGCE primary antibodies
Description: Rabbit polyclonal antibody to SGCE.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human SGCE.
Protein Length: 437
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Tissue Specificity: Ubiquitous.
Involvement in Disease: Dystonia 11, myoclonic: A myoclonic dystonia. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures. DYT11 is characterized by involuntary lightning jerks and dystonic movements and postures alleviated by alcohol. Inheritance is autosomal dominant. The age of onset, pattern of body involvement, presence of myoclonus and response to alcohol are all variable.
Sequence Similarities: Belongs to the sarcoglycan alpha/epsilon family.
Post-Translational Modification: N-glycosylated.
Cellular Location: Cell membrane > Sarcolemma. Cytoplasm > Cytoskeleton. Cell projection > Dendrite. Golgi apparatus.
Database Links:
  • Entrez Gene: 8910?Human
  • Entrez Gene: 20392?Mouse
  • Entrez Gene: 432360?Rat
  • Omim: 604149?Human
  • SwissProt: O43556?Human
  • SwissProt: O70258?Mouse
  • SwissProt: Q6YAT4?Rat
  • Unigene: 371199?Human
  • Unigene: 8739?Mouse
  • Unigene: 185815?Rat
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    Synonyms:
  • dystonia 11, myoclonic Antibody
  • DYT11 Antibody
  • Epsilon sarcoglycan Antibody
  • Epsilon SG Antibody
  • Epsilon-sarcoglycan Antibody
  • Epsilon-SG Antibody
  • ESG Antibody
  • sarcoglycan, epsilon Antibody
  • SGCE Antibody
  • SGCE_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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