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Anti-SGCD Antibody

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产品名称: Anti-SGCD Antibody
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简单介绍

Anti-SGCD Antibody


Anti-SGCD Antibody  的详细介绍
Name: Anti-SGCD Antibody
See all SGCD primary antibodies
Description: Rabbit polyclonal antibody to SGCD.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human SGCD.
Protein Length: 289 (290)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Tissue Specificity: Most strongly expressed in skeletal and cardiac muscle. Also detected in smooth muscle. Weak expression in brain and lung.
Involvement in Disease: Limb-girdle muscular dystrophy 2F: An autosomal recessive degenerative myopathy initially affecting the proximal limb girdle musculature. Muscle from patients shows a complete loss of delta-sarcoglycan as well as of the others components of the sarcoglycan complex.

Cardiomyopathy, dilated 1L: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
Sequence Similarities: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
Post-Translational Modification: Glycosylated.
Cellular Location: Cell membrane > Sarcolemma. Cytoplasm > Cytoskeleton.
Database Links:
  • Entrez Gene: 6444?Human
  • Entrez Gene: 24052?Mouse
  • Omim: 601411?Human
  • SwissProt: Q92629?Human
  • SwissProt: P82347?Mouse
  • Unigene: 387207?Human
  • Unigene: 644733?Human
  • Unigene: 338890?Mouse
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    Synonyms:
  • 35 kDa dystrophin associated glycoprotein Antibody
  • 35 kDa dystrophin-associated glycoprotein Antibody
  • 35DAG Antibody
  • CMD1L Antibody
  • DAGD Antibody
  • delta Sarcoglycan Antibody
  • Delta-sarcoglycan Antibody
  • Delta-SG Antibody
  • Dystrophin associated glycoprotein delta sarcoglycan Antibody
  • LGMD2F Antibody
  • MGC22567 Antibody
  • Placental delta sarcoglycan Antibody
  • Sarcoglycan delta (35 kDa dystrophin associated glycoprotein) Antibody
  • SG delta Antibody
  • SGCD Antibody
  • SGCDP Antibody
  • SGCD_HUMAN Antibody
  • SGD Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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