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Anti-Serum paraoxonase / arylesterase 1 Antibody

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产品名称: Anti-Serum paraoxonase / arylesterase 1 Antibody
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Anti-Serum paraoxonase / arylesterase 1 Antibody


Anti-Serum paraoxonase / arylesterase 1 Antibody  的详细介绍
Name: Anti-Serum paraoxonase / arylesterase 1 Antibody
See all Serum paraoxonase primary antibodies
Description: Rabbit polyclonal antibody to Serum paraoxonase / arylesterase 1
Specificity: The antibody detects endogenous level of total Serum paraoxonase / arylesterase 1 polyclonal antibody.
Applications: WB, IHC
Reactivity: Human
Immunogen: Recombinant Human Serum paraoxonase / arylesterase 1 protein
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
Concentration: 1.0mg / mL
Formulation: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Storage: Store at -20?C
Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Tissue Specificity: Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas.
Involvement in Disease: Microvascular complications of diabetes 5: Pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic *****s. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.
Sequence Similarities: Belongs to the paraoxonase family.
Post-Translational Modification: Glycosylated.
Cellular Location: Secreted > Extracellular space.
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