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Anti-SERPINH1 Antibody

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产品名称: Anti-SERPINH1 Antibody
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Anti-SERPINH1 Antibody


Anti-SERPINH1 Antibody  的详细介绍
Name: Anti-SERPINH1 Antibody
See all SERPINH1 primary antibodies
Description: Rabbit polyclonal antibody to SERPINH1
Specificity: SERPINH1 pAb detects endogenous levels of SERPINH1 protein.
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human SERPINH1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~46 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.
Involvement in Disease: Osteogenesis imperfecta 10: A form of osteogenesis imperfecta, a connective tissue disorder characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI10 is an autosomal recessive form characterized by multiple bone deformities and fractures, generalized osteopenia, dentinogenesis imperfecta, and blue sclerae.
Sequence Similarities: Belongs to the serpin family.
Cellular Location: Endoplasmic reticulum lumen.
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