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Anti-SDCBP2 Antibody

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产品名称: Anti-SDCBP2 Antibody
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简单介绍

Anti-SDCBP2 Antibody


Anti-SDCBP2 Antibody  的详细介绍
Name: Anti-SDCBP2 Antibody
See all SDCBP2 primary antibodies
Description: Goat polyclonal antibody to SDCBP2.
Applications: ELISA, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human SDCBP2 (C terminal).
Sequence: C-LLHHTMDHSIPDA
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival (PubMed:15961997).
Tissue Specificity: Preferentially expressed in cells of the digestive tract (PubMed:11102519). Low expression in skeletal muscle and kidney (PubMed:11102519). Detected in differentiated keratinocytes of normal and malignant epithelium (PubMed:22623796). In healthy skin, expression is localized in suprabasal epidermal layers (PubMed:22623796).
Cellular Location: Cytoplasm. Nucleus > Nucleolus. Nucleus > Nucleoplasm. Cell membrane. Nucleus speckle.

Associates with intracellular membranes and enriched in the apical region of the cell and in intracellular compartments (PubMed:11102519). Colocalizes with TM4SF1 in the apical region of the cell (PubMed:11102519). Predominantly targeted to nuclear PIP2 pools. Shuttles between several subcellular compartments (PubMed:15961997). PIP2 plays an important role in the distribution of SDCBP2 (PubMed:23300061).
Database Links:
  • Entrez Gene: 27111?Human
  • GenBank: NP_056500?Human
  • GenBank: NP_536737?Human
  • Omim: 602217?Human
  • SwissProt: Q9H190?Human
  • Unigene: 657015?Human
    		•
    Synonyms:
  • MDA9 Antibody
  • Melanoma differentiation associated gene 9 Antibody
  • Pro TGF alpha cytoplasmic domain interacting protein 18 Antibody
  • SDCB2_HUMAN Antibody
  • SDCBP2 Antibody
  • SITAC Antibody
  • SITAC18 Antibody
  • ST 2 Antibody
  • Syndecan binding protein (syntenin) 2 Antibody
  • Syndecan binding protein 2 Antibody
  • Syndecan-binding protein 2 Antibody
  • Syntenin 2 Antibody
  • Syntenin-2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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