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Anti-SCO1 Antibody

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产品名称: Anti-SCO1 Antibody
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简单介绍

Anti-SCO1 Antibody


Anti-SCO1 Antibody  的详细介绍
Name: Anti-SCO1 Antibody
See all SCO1 primary antibodies
Description: Rabbit polyclonal antibody to SCO1
Specificity: SCO1 polyclonal antibody detects endogenous levels of SCO1 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Recombinant full length Human SCO1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 34 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: Thought to play a role in cellular copper homeostasis, mitochondrial redox signaling or insertion of copper into the active site of COX.
Tissue Specificity: Predominantly expressed in tissues characterized by high rates of oxidative phosphorylation (OxPhos), including muscle, heart, and brain.
Involvement in Disease: Mitochondrial complex IV deficiency: A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, exercise intolerance, developmental delay, delayed motor development and mental retardation. Some affected individuals manifest a fatal hypertrophic cardiomyopathy resulting in neonatal death. A subset of patients manifest Leigh syndrome.
Sequence Similarities: Belongs to the SCO1/2 family.
Cellular Location: Mitochondrion.
Database Links:
  • Entrez Gene: 6341?Human
  • Omim: 603644?Human
  • SwissProt: O75880?Human
  • Unigene: 14511?Human
    		•
    Synonyms:
  • Cytochrome oxidase deficient homolog Antibody
  • Cytochrome oxidase deficient homolog 1 Antibody
  • Protein SCO1 homolog mitochondrial Antibody
  • Protein SCO1 homolog, mitochondrial Antibody
  • SCO (cytochrome oxidase deficient yeast) homolog 1 Antibody
  • SCO cytochrome oxidase deficient homolog 1 Antibody
  • SCO cytochrome oxidase deficient homolog 1 (yeast) Antibody
  • SCO1 Antibody
  • SCO1_HUMAN Antibody
  • SCOD1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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