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Anti-SAMSN1 Antibody

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产品名称: Anti-SAMSN1 Antibody
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简单介绍

Anti-SAMSN1 Antibody


Anti-SAMSN1 Antibody  的详细介绍
Name: Anti-SAMSN1 Antibody
See all SAMSN1 primary antibodies
Description: Goat polyclonal antibody to SAMSN1.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human SAMSN1 (N terminal).
Sequence: IRLDTLSASLGRSC
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation (By similarity).
Tissue Specificity: Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.
Cellular Location: Nucleus. Cytoplasm. Cell projection > Ruffle.

Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles (By similarity).
Database Links:
  • Entrez Gene: 64092 Human
  • Omim: 607978 Human
  • SwissProt: Q9NSI8 Human
  • Unigene: 473341 Human
  • Unigene: 719474 Human
    		•
    Synonyms:
  • HACS1 Antibody
  • Hematopoietic adapter containing SH3 and sterile α motif (SAM) domains 1 Antibody
  • Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1 Antibody
  • Hematopoietic adaptor containing SH3 and SAM domains 1 Antibody
  • Nash1 Antibody
  • Nuclear localization signals SAM and SH3 domain containing 1 Antibody
  • SAM and SH3 domain containing 2 Antibody
  • SAM domain Antibody
  • SAM domain containing protein SAMSN 1 Antibody
  • SAM domain SH3 domain and nuclear localisation signals 1 Antibody
  • SAM domain SH3 domain and nuclear localization signals 1 Antibody
  • SAM domain, SH3 domain and nuclear localization signals protein 1 Antibody
  • SAM domain-containing protein SAMSN-1 Antibody
  • SAMN1_HUMAN Antibody
  • SAMSN 1 Antibody
  • SAMSN1 Antibody
  • SASH2 Antibody
  • SH3 domain and nuclear localisation signals 1 Antibody
  • SH3 domain and nuclear localization signals protein 1 Antibody
  • SH3 SAM adaptor protein Antibody
  • SH3-SAM adaptor protein Antibody
  • SH3D6B Antibody
  • SLy2 Antibody
  • Src homology domain 3 (SH3) containing adapter protein SH3 lymphocyte protein 2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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