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Anti-RUVBL1 Antibody

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产品名称: Anti-RUVBL1 Antibody
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简单介绍

Anti-RUVBL1 Antibody


Anti-RUVBL1 Antibody  的详细介绍
Name: Anti-RUVBL1 Antibody
See all RUVBL1 primary antibodies
Description: Rabbit polyclonal antibody to RUVBL1.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:20 - 1:50.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human RUVBL1.
Protein Length: 456
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.
Tissue Specificity: Ubiquitously expressed with high expression in heart, skeletal muscle and testis.
Sequence Similarities: Belongs to the RuvB family.
Cellular Location: Nucleus matrix. Nucleus > Nucleoplasm. Cytoplasm. Membrane. Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome.

Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol, although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization. In anaphase it accumulates at the zone of tubule interdigitation. In telophase it is found at polar tubule overlap, and it reappears at the site of chromosomal decondensation in the daughter cells.
Database Links:
  • Entrez Gene: 8607?Human
  • Entrez Gene: 56505?Mouse
  • Entrez Gene: 65137?Rat
  • Omim: 603449?Human
  • SwissProt: Q9Y265?Human
  • SwissProt: P60122?Mouse
  • SwissProt: P60123?Rat
  • Unigene: 272822?Human
  • Unigene: 42195?Mouse
  • Unigene: 86410?Rat
    		•
    Synonyms:
  • 49 kDa TATA box binding protein interacting protein Antibody
  • 49 kDa TATA box-binding protein-interacting protein Antibody
  • 49 kDa TBP interacting protein Antibody
  • 49 kDa TBP-interacting protein Antibody
  • 54 kDa erythrocyte cytosolic protein Antibody
  • ECP-54 Antibody
  • ECP54 Antibody
  • ERYTHROCYTE CYTOSOLIC PROTEIN, 54-KD Antibody
  • INO80 complex subunit H Antibody
  • NMP 238 Antibody
  • Nuclear matrix protein 238 Antibody
  • PONTIN Antibody
  • Pontin 52 Antibody
  • RuvB like 1 Antibody
  • RuvB like AAA ATPase 1 Antibody
  • RuvB-like 1 Antibody
  • RUVB1_HUMAN Antibody
  • RUVBL1 Antibody
  • RVB1 Antibody
  • TAP54 alpha Antibody
  • TAP54-alpha Antibody
  • TIP49 Antibody
  • TIP49A Antibody
  • TIP60 associated protein 54 alpha Antibody
  • TIP60-associated protein 54-alpha Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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