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Anti-RPS6 (phospho-S240) Antibody

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产品名称: Anti-RPS6 (phospho-S240) Antibody
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Anti-RPS6 (phospho-S240) Antibody


Anti-RPS6 (phospho-S240) Antibody  的详细介绍
Name: Anti-RPS6 (phospho-S240) Antibody
See all RPS6 primary antibodies
Description: Rabbit polyclonal antibody to RPS6 (phospho-S240)
Specificity: p-Ribosomal Protein S6 (S240) pAb detects endogenous levels of Ribosomal Protein S6 protein only when phosphorylated at Ser240
Applications: WB, IHC, IF
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic phosphopeptide derived from human Ribosomal Protein S6 around the phosphorylation site of Serine 240.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 29 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA.
Sequence Similarities: Belongs to the ribosomal protein S6e family.
Post-Translational Modification: Ribosomal protein S6 is the major substrate of protein kinases in eukaryote ribosomes. The phosphorylation is stimulated by growth factors, tumor promoting agents, and mitogens. It is dephosphorylated at growth arrest. Phosphorylated at Ser-235 and Ser-236 by RPS6KA1 and RPS6KA3; phosphorylation at these sites facilitates the assembly of the preinitiation complex.
Database Links:
  • Entrez Gene: 6194?Human
  • Entrez Gene: 20104?Mouse
  • Entrez Gene: 667739?Mouse
  • Entrez Gene: 29304?Rat
  • Omim: 180460?Human
  • SwissProt: P62753?Human
  • SwissProt: P62754?Mouse
  • SwissProt: P62755?Rat
  • Unigene: 408073?Human
  • Unigene: 379007?Mouse
  • Unigene: 425090?Mouse
  • Unigene: 34341?Rat
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    Synonyms:
  • 40S ribosomal protein S6 Antibody
  • Air8 Antibody
  • NP33 Antibody
  • Phosphoprotein NP33 Antibody
  • Pp30 Antibody
  • Ribosomal protein S6 Antibody
  • RP S6 Antibody
  • RPS6 Antibody
  • RS6 Antibody
  • RS6_HUMAN Antibody
  • S6 Antibody
  • S6 Ribosomal Protein Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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