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Anti-RPS10 Antibody

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产品名称: Anti-RPS10 Antibody
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简单介绍

Anti-RPS10 Antibody


Anti-RPS10 Antibody  的详细介绍
Name: Anti-RPS10 Antibody
See all RPS10 primary antibodies
Description: Rabbit polyclonal antibody to RPS10
Specificity: The antibody detects endogenous levels of total RPS10 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein of human RPS10
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Component of the 40S ribosomal subunit.
Involvement in Disease: Diamond-Blackfan anemia 9: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Sequence Similarities: Belongs to the ribosomal protein S10e family.
Post-Translational Modification: Methylated by PRMT5. Methylation is necessary for its interaction with NPS1, its localization in the granular component (GC) region of the nucleolus, for the proper assembly of ribosomes, protein synthesis and optimal cell proliferation.
Cellular Location: Cytoplasm. Nucleus > Nucleolus.

Localized in the granular component (GC) region of the nucleolus. Methylation is required for its localization in the GC region. Colocalizes with NPS1 in the GC region of the nucleolus.
Database Links:
  • Entrez Gene: 6204?Human
  • Omim: 603632?Human
  • SwissProt: P46783?Human
  • Unigene: 406620?Human
  • Unigene: 645317?Human
    		•
    Synonyms:
  • 40S ribosomal protein S10 Antibody
  • DBA9 Antibody
  • MGC88819 Antibody
  • OTTHUMP00000016229 Antibody
  • OTTHUMP00000016230 Antibody
  • Ribosomal protein S10 Antibody
  • RPS10 Antibody
  • RS10_HUMAN Antibody
  • S10 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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