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Anti-RPL35A Antibody

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产品名称: Anti-RPL35A Antibody
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简单介绍

Anti-RPL35A Antibody


Anti-RPL35A Antibody  的详细介绍
Name: Anti-RPL35A Antibody
See all RPL35A primary antibodies
Description: Rabbit polyclonal antibody to RPL35A
Specificity: The antibody detects endogenous levels of total RPL35A protein.
Applications: WB, IHC
Dilutions: Western blotting: 1:200-1:1000 Immunohistochemistry: 1:100-1:200
Reactivity: Human
Immunogen: Full length fusion protein of human RPL35A
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.1mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Required for the proliferation and viability of hematopoietic cells. Plays a role in 60S ribosomal subunit formation. The protein was found to bind to both initiator and elongator tRNAs and consequently was assigned to the P site or P and A site.
Involvement in Disease: Diamond-Blackfan anemia 5: A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Sequence Similarities: Belongs to the ribosomal protein L35Ae family.
Database Links:
  • Entrez Gene: 6165?Human
  • Omim: 180468?Human
  • SwissProt: P18077?Human
  • Unigene: 529631?Human
  • Synonyms:
  • 60S ribosomal protein L35a Antibody
  • Cell growth-inhibiting gene 33 protein Antibody
  • DBA5 Antibody
  • L35A Antibody
  • Ribosomal Protein L35a Antibody
  • RL35A_HUMAN Antibody
  • RPL35A Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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