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Anti-WTAP Antibody

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产品名称: Anti-WTAP Antibody
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简单介绍

Anti-WTAP Antibody


Anti-WTAP Antibody  的详细介绍
Name: Anti-WTAP Antibody
See all WTAP primary antibodies
Description: Rabbit polyclonal antibody to WTAP
Specificity: The antibody detects endogenous levels of total WTAP protein.
Applications: IHC
Reactivity: Human
Immunogen: Full length fusion protein
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification
Concentration: 0.8mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator (PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).
Tissue Specificity: Ubiquitously expressed.
Sequence Similarities: Belongs to the fl(2)d family.
Cellular Location: Nucleus > Nucleoplasm. Nucleus speckle.
Database Links:
  • Entrez Gene: 9589?Human
  • Omim: 605442?Human
  • SwissProt: Q15007?Human
  • Unigene: 446091?Human
    		•
    Synonyms:
  • DKFZp686F20131 Antibody
  • Female-lethal(2)D homolog Antibody
  • FL2D_HUMAN Antibody
  • hFL(2)D Antibody
  • KIAA0105 Antibody
  • MGC3925 Antibody
  • Mum2 Antibody
  • OTTHUMP00000017522 Antibody
  • OTTHUMP00000017523 Antibody
  • PNAS 132 Antibody
  • PNAS-132 Antibody
  • PNAS132 Antibody
  • Pre mRNA splicing regulator WTAP Antibody
  • Pre-mRNA-splicing regulator WTAP Antibody
  • Putative pre mRNA splicing regulator female lethal 2D homolog Antibody
  • Putative pre mRNA splicing regulator female lethal(2D) Antibody
  • Putative pre-mRNA splicing regulator female lethal(2D) homolog Antibody
  • putative pre-mRNA splicing regulator female-lethal(2D) Antibody
  • Wilms tumor 1 associated protein Antibody
  • Wilms tumor 1 associating protein Antibody
  • Wilms tumor 1-associating protein Antibody
  • Wilms' tumor 1 associating protein Antibody
  • Wilms' tumour 1-associating protein Antibody
  • WT1 associated protein Antibody
  • WT1-associated protein Antibody
  • WT1-associating protein Antibody
  • WTAP Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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