产品资料

Anti-WNT3A Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-WNT3A Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-WNT3A Antibody


Anti-WNT3A Antibody  的详细介绍
Name: Anti-WNT3A Antibody
See all WNT3A primary antibodies
Description: Rabbit polyclonal antibody to WNT3A
Specificity: The antibody detects endogenous level of total WNT3A antibody.
Applications: WB
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human WNT3A.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were purified by affinity purification using immunogen.
Concentration: 1.0mg / ml
Formulation: Supplied at 1.0mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
Tissue Specificity: Moderately expressed in placenta and at low levels in ***** lung, spleen, and prostate.
Sequence Similarities: Belongs to the Wnt family.
Post-Translational Modification: Palmitoleylation by PORCN is required for efficient binding to frizzled receptors. Palmitoleylation is required for proper trafficking to cell surface, vacuolar acidification is critical to release palmitoleylated WNT3A from WLS in secretory vesicles (PubMed:20826466, PubMed:21244856, PubMed:24292069). Depalmitoleylated by NOTUM, leading to inhibit Wnt signaling pathway, possibly by promoting disulfide bond formation and oligomerization (PubMed:25731175).
Cellular Location: Secreted > Extracellular space > Extracellular matrix.
Database Links:
  • Entrez Gene: 89780 Human
  • Entrez Gene: 22416 Mouse
  • Omim: 606359 Human
  • SwissProt: P56704 Human
  • SwissProt: P27467 Mouse
  • Unigene: 336930 Human
  • Unigene: 1367 Mouse
    		•
    Synonyms:
  • Protein Wnt 3a Precursor Antibody
  • Protein Wnt-3a Antibody
  • Wingless type MMTV integration site family member 3A Antibody
  • Wnt 3a Antibody
  • Wnt3a Antibody
  • WNT3A protein Antibody
  • WNT3A_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号