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Anti-WNT2B Antibody

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产品名称: Anti-WNT2B Antibody
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简单介绍

Anti-WNT2B Antibody


Anti-WNT2B Antibody  的详细介绍
Name: Anti-WNT2B Antibody
See all WNT2B primary antibodies
Description: Rabbit polyclonal antibody to WNT2B
Specificity: The antibody detects endogenous levels of total WNT2B protein.
Applications: IHC
Reactivity: Human
Immunogen: Synthetic peptide of human wingless-type MMTV integration site family, member 2B
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 0.8mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis.
Tissue Specificity: Isoform 1 is expressed in ***** heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the ***** brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.
Sequence Similarities: Belongs to the Wnt family.
Post-Translational Modification: Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition.
Cellular Location: Secreted > Extracellular space > Extracellular matrix.
Database Links:
  • Entrez Gene: 7482?Human
  • Omim: 601968?Human
  • SwissProt: Q93097?Human
  • Unigene: 258575?Human
    		•
    Synonyms:
  • Protein Wnt-13 Antibody
  • Protein Wnt-2b Antibody
  • Wingless type MMTV integration site family, member 13 Antibody
  • Wingless type MMTV integration site family, member 2B Antibody
  • WNT13 Antibody
  • Wnt2b Antibody
  • WNT2B_HUMAN Antibody
  • XWNT2 Antibody
  • XWNT2, Xenopus, homolog of Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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