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Anti-WISP1 Antibody

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产品名称: Anti-WISP1 Antibody
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简单介绍

Anti-WISP1 Antibody


Anti-WISP1 Antibody  的详细介绍
Name: Anti-WISP1 Antibody
See all WISP1 primary antibodies
Description: Goat polyclonal antibody to WISP1.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human WISP1 (C terminal).
Sequence: C-ESYPDFSEIAN
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
Tissue Specificity: Expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Isoform 2 is expressed predominantly in scirrhous gastric carcinoma and, weakly in placenta. Overexpression is associated with several cancers including breast cancer and colon tumors. Isoform 2 is overexpressed in scirrhous gastric carcinoma.
Sequence Similarities: Belongs to the CCN family.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 8840 Human
  • Omim: 603398 Human
  • SwissProt: O95388 Human
  • Unigene: 492974 Human
    		•
    Synonyms:
  • CCN 4 Antibody
  • CCN family member 4 Antibody
  • CCN4 Antibody
  • WISP 1 Antibody
  • WISP 1c Antibody
  • WISP 1i Antibody
  • WISP 1tc Antibody
  • WISP1 Antibody
  • WISP1c Antibody
  • WISP1i Antibody
  • WISP1tc Antibody
  • Wnt 1 induced secreted protein Antibody
  • WNT 1 induced secreted protein 1 Antibody
  • WNT 1 inducible signaling pathway protein 1 Antibody
  • Wnt 1 signaling pathway protein 1 Antibody
  • Wnt-1 inducible signaling pathway protein 1 Antibody
  • Wnt1 induced secreted protein Antibody
  • WNT1 induced secreted protein 1 Antibody
  • WNT1 inducible signaling pathway protein 1 Antibody
  • Wnt1 signaling pathway protein 1 Antibody
  • WNT1-inducible-signaling pathway protein 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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