产品资料

Anti-WISP1 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-WISP1 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-WISP1 Antibody


Anti-WISP1 Antibody  的详细介绍
Name: Anti-WISP1 Antibody
See all WISP1 primary antibodies
Description: Rabbit polyclonal antibody to WISP1.
Applications: WB
Dilutions: WB: 1:500 - 1:2000.
Reactivity: Human, Mouse
Immunogen: Recombinant protein of human WISP1.
Protein Length: 367
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X(L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.
Tissue Specificity: Expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Isoform 2 is expressed predominantly in scirrhous gastric carcinoma and, weakly in placenta. Overexpression is associated with several cancers including breast cancer and colon tumors. Isoform 2 is overexpressed in scirrhous gastric carcinoma.
Sequence Similarities: Belongs to the CCN family.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 8840 Human
  • Entrez Gene: 22402 Mouse
  • Omim: 603398 Human
  • SwissProt: O95388 Human
  • SwissProt: O54775 Mouse
  • Unigene: 492974 Human
  • Unigene: 10222 Mouse
    		•
    Synonyms:
  • CCN 4 Antibody
  • CCN family member 4 Antibody
  • CCN4 Antibody
  • WISP 1 Antibody
  • WISP 1c Antibody
  • WISP 1i Antibody
  • WISP 1tc Antibody
  • WISP1 Antibody
  • WISP1c Antibody
  • WISP1i Antibody
  • WISP1tc Antibody
  • Wnt 1 induced secreted protein Antibody
  • WNT 1 induced secreted protein 1 Antibody
  • WNT 1 inducible signaling pathway protein 1 Antibody
  • Wnt 1 signaling pathway protein 1 Antibody
  • Wnt-1 inducible signaling pathway protein 1 Antibody
  • Wnt1 induced secreted protein Antibody
  • WNT1 induced secreted protein 1 Antibody
  • WNT1 inducible signaling pathway protein 1 Antibody
  • Wnt1 signaling pathway protein 1 Antibody
  • WNT1-inducible-signaling pathway protein 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号