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Anti-WIPI2 Antibody

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产品名称: Anti-WIPI2 Antibody
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Anti-WIPI2 Antibody


Anti-WIPI2 Antibody  的详细介绍
Name: Anti-WIPI2 Antibody
See all WIPI2 primary antibodies
Description: Rabbit polyclonal antibody to WIPI2.
Applications: WB, IHC
Dilutions: WB: 1:200 - 1:2000, IHC: 1:50 - 1:200.
Reactivity: Human
Immunogen: A synthetic peptide of human WIPI2.
Protein Length: 454
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Early component of the autophagy machinery being involved in formation of preautophagosomal structures and their maturation into mature phagosomes in response to phosphatidylinositol 3-phosphate (PtdIns3P). May bind PtdIns3P.
Tissue Specificity: Ubiquitously expressed (at protein level). Highly expressed in heart, skeletal muscle and pancreas. Expression is down-regulated in pancreatic and in kidney tumors.
Sequence Similarities: Belongs to the WD repeat SVP1 family.
Cellular Location: Preautophagosomal structure membrane.

Localizes to omegasomes membranes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Enriched at preautophagosomal structure membranes in response to PtdIns3P.
Database Links:
  • Entrez Gene: 26100?Human
  • Omim: 609225?Human
  • SwissProt: Q9Y4P8?Human
  • Unigene: 122363?Human
    		•
    Synonyms:
  • ATG18B Antibody
  • Atg21 Antibody
  • CGI 50 Antibody
  • DKFZp434J154 Antibody
  • DKFZp686P02188 Antibody
  • FLJ12979 Antibody
  • FLJ14217 Antibody
  • FLJ42984 Antibody
  • WD repeat domain phosphoinositide-interacting protein 2 Antibody
  • WD repeat domain, phosphoinositide interacting 2 Antibody
  • WD40 repeat protein interacting with phosphoinositides 2 Antibody
  • WIPI 2 Antibody
  • WIPI-2 Antibody
  • WIPI2 Antibody
  • WIPI2_HUMAN Antibody
  • WIPI49 like protein 2 Antibody
  • WIPI49-like protein 2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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