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Anti-WDR68 Antibody

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产品名称: Anti-WDR68 Antibody
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简单介绍

Anti-WDR68 Antibody


Anti-WDR68 Antibody  的详细介绍
Name: Anti-WDR68 Antibody
See all WDR68 primary antibodies
Description: Rabbit polyclonal antibody to WDR68
Specificity: WDR68 polyclonal antibody detects endogenous levels of WDR68 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human WDR68.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 39 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Sequence Similarities: Belongs to the WD repeat DCAF7 family.
Cellular Location: Cytoplasm. Nucleus.

Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm.
Database Links:
  • Entrez Gene: 10238?Human
  • Entrez Gene: 71833?Mouse
  • Entrez Gene: 303602?Rat
  • Omim: 605973?Human
  • SwissProt: P61962?Human
  • SwissProt: P61963?Mouse
  • Unigene: 410596?Human
  • Unigene: 307455?Mouse
    		•
    Synonyms:
  • AN11 Antibody
  • Dcaf7 Antibody
  • DCAF7_HUMAN Antibody
  • DDB1- and CUL4-associated factor 7 Antibody
  • HAN11 Antibody
  • Human anthocyanin Antibody
  • Petunia Antibody
  • Seven WD repeat protein of the AN11 family 1 Antibody
  • SWAN 1 Antibody
  • WD repeat domain 68 Antibody
  • WD repeat protein An11 homolog Antibody
  • WD repeat-containing protein 68 Antibody
  • WD repeat-containing protein An11 homolog Antibody
  • WDR68 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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