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Anti-WDR5 Antibody

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产品名称: Anti-WDR5 Antibody
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简单介绍

Anti-WDR5 Antibody


Anti-WDR5 Antibody  的详细介绍
Name: Anti-WDR5 Antibody
See all WDR5 primary antibodies
Description: Rabbit polyclonal antibody to WDR5
Specificity: WDR5 pAb detects endogenous levels of WDR5 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human WDR5.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~36 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
Sequence Similarities: Belongs to the WD repeat WDR5/wds family.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 11091?Human
  • Entrez Gene: 140858?Mouse
  • Entrez Gene: 362093?Rat
  • Omim: 609012?Human
  • SwissProt: P61964?Human
  • SwissProt: P61965?Mouse
  • SwissProt: Q498M4?Rat
  • Unigene: 397638?Human
  • Unigene: 28265?Mouse
  • Unigene: 106818?Rat
    		•
    Synonyms:
  • 2410008O07Rik Antibody
  • AA408785 Antibody
  • AA960360 Antibody
  • Big Antibody
  • BIG 3 Antibody
  • BIG3 Antibody
  • BMP2 induced 3 kb gene protein Antibody
  • BMP2 induced gene, 3-KB Antibody
  • BMP2-induced 3-kb gene protein Antibody
  • MGC114572 Antibody
  • OTTHUMP00000162494 Antibody
  • SWD 3 Antibody
  • SWD3 Antibody
  • SWD3 Set1c WD40 repeat protein homolog Antibody
  • WD repeat containing protein 5 Antibody
  • WD repeat domain 5 Antibody
  • WD repeat protein 5 Antibody
  • WD repeat-containing protein 5 Antibody
  • WD repeat-containing protein BIG-3 Antibody
  • WDR 5 Antibody
  • WDR5 Antibody
  • WDR5_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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