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Anti-Hexim1 Antibody

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产品名称: Anti-Hexim1 Antibody
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简单介绍

Anti-Hexim1 Antibody


Anti-Hexim1 Antibody  的详细介绍
Name: Anti-Hexim1 Antibody
See all Hexim1 primary antibodies
Description: Rabbit polyclonal antibody to Hexim1
Specificity: Hexim1 Polyclonal Antibody detects endogenous levels of Hexim1 protein.
Applications: WB, IHC, IF, ELISA
Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from the Internal region of human Hexim1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1mg / ml
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20?C / 1 year
Function: Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
Tissue Specificity: Ubiquitously expressed with higher expression in placenta. HEXIM1 and HEXIM2 are differentially expressed. Expressed in endocrine tissues.
Sequence Similarities: Belongs to the HEXIM family.
Cellular Location: Nucleus. Cytoplasm.

Binds alpha-importin and is mostly nuclear (PubMed:16362050).
Database Links:
  • Entrez Gene: 10614?Human
  • Entrez Gene: 192231?Mouse
  • Entrez Gene: 498008?Rat
  • Omim: 607328?Human
  • SwissProt: O94992?Human
  • SwissProt: Q8R409?Mouse
  • SwissProt: Q5M9G1?Rat
  • Unigene: 15299?Human
  • Unigene: 586945?Human
  • Unigene: 634944?Human
  • Unigene: 741758?Human
  • Unigene: 8763?Mouse
  • Unigene: 113703?Rat
  • Synonyms:
  • Cardiac lineage protein 1 Antibody
  • CLP 1 Antibody
  • CLP1 Antibody
  • EDG 1 Antibody
  • EDG1 Antibody
  • Estrogen down-regulated gene 1 protein Antibody
  • FLJ13562 Antibody
  • Hexamethylene bis acetamide inducible 1 Antibody
  • Hexamethylene bis acetamide inducible protein Antibody
  • Hexamethylene bis acetamide inducible transcript 1 Antibody
  • Hexamethylene bis-acetamide-inducible protein 1 Antibody
  • HEXI1_HUMAN Antibody
  • HEXIM 1 Antibody
  • HEXIM1 Antibody
  • HEXIM1 protein Antibody
  • HIS 1 Antibody
  • HIS1 Antibody
  • HMBA inducible Antibody
  • MAQ 1 Antibody
  • MAQ1 Antibody
  • Menage a quatre 1 Antibody
  • Menage a quatre protein 1 Antibody
  • Protein HEXIM1 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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