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Anti-HES6 Antibody

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产品名称: Anti-HES6 Antibody
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简单介绍

Anti-HES6 Antibody


Anti-HES6 Antibody  的详细介绍
Name: Anti-HES6 Antibody
See all HES6 primary antibodies
Description: Rabbit polyclonal antibody to HES6
Specificity: The antibody detects endogenous levels of total HES6.
Applications: WB
Reactivity: Human
Immunogen: Synthesized peptide derived from N-terminal of human HES6.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up-regulate transcription in its presence. Promotes cell differentiation (By similarity).
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 55502 Human
  • Omim: 610331 Human
  • SwissProt: Q96HZ4 Human
  • Unigene: 42949 Human
    		•
    Synonyms:
  • bHLHb41 Antibody
  • bHLHc23 Antibody
  • C HAIRY1 Antibody
  • Class B basic helix-loop-helix protein 41 Antibody
  • Hairy and enhancer of split 6 Antibody
  • Hairy/enhancer of split 6, Drosophila, homolog of, 6 Antibody
  • HES 6 Antibody
  • hes family bHLH transcription factor 6 Antibody
  • HES6 Antibody
  • Transcription cofactor HES6 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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