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Anti-HES1 Antibody

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产品名称: Anti-HES1 Antibody
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简单介绍

Anti-HES1 Antibody


Anti-HES1 Antibody  的详细介绍
Name: Anti-HES1 Antibody
See all HES1 primary antibodies
Description: Rabbit polyclonal antibody to HES1
Specificity: The antibody detects endogenous levels of total HES1 protein.
Applications: WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to residues near the C terminal of human hes family bHLH transcription factor 1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 0.7mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20˚C
Function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 3280 Human
  • Omim: 139605 Human
  • SwissProt: Q14469 Human
  • Unigene: 250666 Human
    		•
    Synonyms:
  • bHLHb39 Antibody
  • C-HAIRY1 Antibody
  • c-hairy1A Antibody
  • Class B basic helix-loop-helix protein 39 Antibody
  • FLJ20408 Antibody
  • Hairy and enhancer of split 1 Antibody
  • Hairy and enhancer of split 1 (Drosophila) Antibody
  • Hairy homolog Antibody
  • Hairy homolog (Drosophila) Antibody
  • Hairy like Antibody
  • Hairy, Drosophila, homolog of Antibody
  • Hairy-like protein Antibody
  • Hairy/enhancer of split, Drosophila, homolog of, 1 Antibody
  • HAIRY1 Antibody
  • HES-1 Antibody
  • Hes1 Antibody
  • Hes1 hairy and enhancer of split 1 (Drosophila) Antibody
  • HES1_HUMAN Antibody
  • HHL Antibody
  • HL Antibody
  • HRY Antibody
  • MGC129109 Antibody
  • OTTHUMP00000209031 Antibody
  • RHL Antibody
  • Transcription factor HES-1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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