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Anti-HES1 Antibody

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产品名称: Anti-HES1 Antibody
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简单介绍

Anti-HES1 Antibody


Anti-HES1 Antibody  的详细介绍
Name: Anti-HES1 Antibody
See all HES1 primary antibodies
Description: Rabbit polyclonal antibody to HES1.
Applications: WB, IHC, ICC, FC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, ICC: 1:50 - 1:200, FC: 1:20 - 1:50.
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic peptide of human HES1.
Protein Length: 280
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 3280?Human
  • Entrez Gene: 15205?Mouse
  • Entrez Gene: 29577?Rat
  • Omim: 139605?Human
  • SwissProt: Q14469?Human
  • SwissProt: P35428?Mouse
  • SwissProt: Q04666?Rat
  • Unigene: 250666?Human
  • Unigene: 390859?Mouse
  • Unigene: 19727?Rat
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    Synonyms:
  • bHLHb39 Antibody
  • C-HAIRY1 Antibody
  • c-hairy1A Antibody
  • Class B basic helix-loop-helix protein 39 Antibody
  • FLJ20408 Antibody
  • Hairy and enhancer of split 1 Antibody
  • Hairy and enhancer of split 1 (Drosophila) Antibody
  • Hairy homolog Antibody
  • Hairy homolog (Drosophila) Antibody
  • Hairy like Antibody
  • Hairy, Drosophila, homolog of Antibody
  • Hairy-like protein Antibody
  • Hairy/enhancer of split, Drosophila, homolog of, 1 Antibody
  • HAIRY1 Antibody
  • HES-1 Antibody
  • Hes1 Antibody
  • Hes1 hairy and enhancer of split 1 (Drosophila) Antibody
  • HES1_HUMAN Antibody
  • HHL Antibody
  • HL Antibody
  • HRY Antibody
  • MGC129109 Antibody
  • OTTHUMP00000209031 Antibody
  • RHL Antibody
  • Transcription factor HES-1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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