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Anti-HES-1 Antibody

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产品名称: Anti-HES-1 Antibody
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简单介绍

Anti-HES-1 Antibody


Anti-HES-1 Antibody  的详细介绍
Name: Anti-HES-1 Antibody
See all HES-1 primary antibodies
Description: Rabbit polyclonal antibody to HES-1
Specificity: Not yet tested in other species.
Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Immunogen: 15 amino acid peptide from near the N terminal residues of human HES-1 protein.The peptide sequence is: CDALKKDSSRHSKLEK
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Affinity purified
Concentration: 1.0mg / ml
Formulation: PBS, pH 7.4 with 0.02% Sodium Azide
Storage: This product is stable for several weeks at 4˚C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20˚C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Function: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
Tissue Specificity: Present in all tissues examined but highest in epithelial cells and in mesoderm-derived tissues such as embryonal muscle cells.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 3280 Human
  • Entrez Gene: 15205 Mouse
  • Entrez Gene: 29577 Rat
  • Omim: 139605 Human
  • SwissProt: Q14469 Human
  • SwissProt: P35428 Mouse
  • SwissProt: Q04666 Rat
  • Unigene: 250666 Human
  • Unigene: 390859 Mouse
  • Unigene: 19727 Rat
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    Synonyms:
  • bHLHb39 Antibody
  • C-HAIRY1 Antibody
  • c-hairy1A Antibody
  • Class B basic helix-loop-helix protein 39 Antibody
  • FLJ20408 Antibody
  • Hairy and enhancer of split 1 Antibody
  • Hairy and enhancer of split 1 (Drosophila) Antibody
  • Hairy homolog Antibody
  • Hairy homolog (Drosophila) Antibody
  • Hairy like Antibody
  • Hairy, Drosophila, homolog of Antibody
  • Hairy-like protein Antibody
  • Hairy/enhancer of split, Drosophila, homolog of, 1 Antibody
  • HAIRY1 Antibody
  • HES-1 Antibody
  • Hes1 Antibody
  • Hes1 hairy and enhancer of split 1 (Drosophila) Antibody
  • HES1_HUMAN Antibody
  • HHL Antibody
  • HL Antibody
  • HRY Antibody
  • MGC129109 Antibody
  • OTTHUMP00000209031 Antibody
  • RHL Antibody
  • Transcription factor HES-1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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