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Anti-HDAC9 Antibody

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产品名称: Anti-HDAC9 Antibody
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Anti-HDAC9 Antibody


Anti-HDAC9 Antibody  的详细介绍
Name: Anti-HDAC9 Antibody
See all HDAC9 primary antibodies
Description: Rabbit polyclonal antibody to HDAC9.
Applications: WB
Dilutions: WB: 1:500 - 1:2000.
Reactivity: Human, Mouse, Rat
Immunogen: A synthetic peptide of human HDAC9.
Protein Length: 1011
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.
Tissue Specificity: Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level).
Sequence Similarities: Belongs to the histone deacetylase family. HD type 2 subfamily.
Post-Translational Modification: Phosphorylated on Ser-220 and Ser-450; which promotes 14-3-3-binding, impairs interaction with MEF2, and antagonizes antimyogenic activity. Phosphorylated on Ser-240; which impairs nuclear accumulation (By similarity). Isoform 7 is phosphorylated on Tyr-1010. Phosphorylated by the PKC kinases PKN1 and PKN2, impairing nuclear import.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 9734 Human
  • Entrez Gene: 687001 Rat
  • Omim: 606543 Human
  • SwissProt: Q9UKV0 Human
  • Unigene: 196054 Human
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    Synonyms:
  • HD 7 Antibody
  • HD 7B Antibody
  • HD 9 Antibody
  • HD7 Antibody
  • HD7B Antibody
  • HD9 Antibody
  • HDAC Antibody
  • HDAC 7 Antibody
  • HDAC 7B Antibody
  • HDAC 9 Antibody
  • HDAC 9B Antibody
  • HDAC 9FL Antibody
  • HDAC7 Antibody
  • HDAC7B Antibody
  • HDAC9 Antibody
  • HDAC9B Antibody
  • HDAC9FL Antibody
  • HDAC9_HUMAN Antibody
  • HDRP Antibody
  • Histone deacetylase 4/5 related protein Antibody
  • Histone deacetylase 7 Antibody
  • Histone deacetylase 7B Antibody
  • Histone deacetylase 9 Antibody
  • Histone deacetylase 9A Antibody
  • Histone deacetylase related protein Antibody
  • Histone deacetylase-related protein Antibody
  • KIAA0744 Antibody
  • MEF2 interacting transcription repressor MITR Antibody
  • MEF2 interacting transcription repressor protein Antibody
  • MEF2-interacting transcription repressor MITR Antibody
  • MITR Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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