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Anti-HDAC6 Antibody

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产品名称: Anti-HDAC6 Antibody
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Anti-HDAC6 Antibody


Anti-HDAC6 Antibody  的详细介绍
Name: Anti-HDAC6 Antibody
See all HDAC6 primary antibodies
Description: Goat polyclonal antibody to HDAC6.
Applications: ELISA, WB
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to Human HDAC6 (C terminal).
Sequence: C-AHQNKFGEDMPHPH
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Tissue Specificity: Expressed in neurons of the cortex. Expressed in Purkinje cells. Detected in keratinocytes (at protein level).
Sequence Similarities: Belongs to the histone deacetylase family. HD type 2 subfamily.
Post-Translational Modification: Phosphorylated by AURKA.
Cellular Location: Nucleus. Cytoplasm. Perikaryon. Cell projection > Dendrite. Cell projection > Axon.

It is mainly cytoplasmic, where it is associated with microtubules.
Database Links:
  • Entrez Gene: 10013 Human
  • Entrez Gene: 15185 Mouse
  • Omim: 300272 Human
  • SwissProt: Q9UBN7 Human
  • SwissProt: Q9Z2V5 Mouse
  • Unigene: 6764 Human
  • Unigene: 29854 Mouse
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    Synonyms:
  • CPBHM Antibody
  • FLJ16239 Antibody
  • HD 6 Antibody
  • HD6 Antibody
  • HDAC 6 Antibody
  • HDAC6 Antibody
  • HDAC6_HUMAN Antibody
  • Histone deacetylase 6 Antibody
  • Histone deacetylase 6 (HD6) Antibody
  • JM 21 Antibody
  • JM21 Antibody
  • KIAA0901 Antibody
  • OTTHUMP00000032398 Antibody
  • OTTHUMP00000197663 Antibody
  • PPP1R90 Antibody
  • Protein phosphatase 1 regulatory subunit 90 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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