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Anti-Separase (phospho-S801) Antibody

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产品名称: Anti-Separase (phospho-S801) Antibody
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Anti-Separase (phospho-S801) Antibody


Anti-Separase (phospho-S801) Antibody  的详细介绍
Name: Anti-Separase (phospho-S801) Antibody
See all Separase primary antibodies
Description: Rabbit polyclonal antibody to Separase (phospho-S801)
Specificity: p-Separase (S801) pAb detects endogenous levels of Separase protein only when phosphorylated at Ser801.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic phosphopeptide derived from human Separase around the phosphorylation site of Serine 801.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 230 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
Post-Translational Modification: Autocleaves. This function, which is not essential for its protease activity, is unknown.
Cellular Location: Cytoplasm. Nucleus.
Database Links:
  • Entrez Gene: 9700?Human
  • Entrez Gene: 105988?Mouse
  • Omim: 604143?Human
  • SwissProt: Q14674?Human
  • SwissProt: P60330?Mouse
  • Unigene: 153479?Human
  • Unigene: 288324?Mouse
    		•
    Synonyms:
  • Caspase like protein ESPL1 Antibody
  • Caspase-like protein ESPL1 Antibody
  • ESP 1 Antibody
  • ESP1 Antibody
  • ESPL 1 Antibody
  • Espl1 Antibody
  • ESPL1_HUMAN Antibody
  • Extra spindle poles like 1 Antibody
  • Extra spindle poles like 1 protein Antibody
  • Extra spindle poles-like 1 protein Antibody
  • FLJ46492 Antibody
  • KIAA0165 Antibody
  • Separase Antibody
  • Separin Antibody
  • Similar to fission yeast cut1and gene Antibody
  • SSE Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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