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Anti-SENP2 Antibody

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产品名称: Anti-SENP2 Antibody
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简单介绍

Anti-SENP2 Antibody


Anti-SENP2 Antibody  的详细介绍
Name: Anti-SENP2 Antibody
See all SENP2 primary antibodies
Description: Rabbit polyclonal antibody to SENP2
Specificity: The antibody detects endogenous levels of total SENP2 protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein of human SENP2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Deconjugates SUMO2 from MTA1. Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (PubMed:20194620).
Sequence Similarities: Belongs to the peptidase C48 family.
Post-Translational Modification: Polyubiquitinated; which leads to proteasomal degradation.
Cellular Location: Nucleus > Nuclear pore complex. Nucleus membrane. Cytoplasm.

Shuttles between cytoplasm and nucleus.
Database Links:
  • Entrez Gene: 59343?Human
  • Omim: 608261?Human
  • SwissProt: Q9HC62?Human
  • Unigene: 401388?Human
  • Synonyms:
  • Axam2 Antibody
  • DKFZp762A2316 Antibody
  • KIAA1331 Antibody
  • SENP2 Antibody
  • SENP2_HUMAN Antibody
  • Sentrin specific protease 2 Antibody
  • Sentrin-specific protease 2 Antibody
  • Sentrin/SUMO specific protease SENP2 Antibody
  • Sentrin/SUMO-specific protease SENP2 Antibody
  • SMT3 specific isopeptidase 2 Antibody
  • SMT3-specific isopeptidase 2 Antibody
  • Smt3ip2 Antibody
  • SUMO1/sentrin/SMT3 specific peptidase 2 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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