产品资料

Anti-SEMA7A Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-SEMA7A Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-SEMA7A Antibody


Anti-SEMA7A Antibody  的详细介绍
Name: Anti-SEMA7A Antibody
See all SEMA7A primary antibodies
Description: Rabbit polyclonal antibody to SEMA7A
Specificity: The antibody detects endogenous levels of total SEMA7A protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.9mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Tissue Specificity: Detected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level). Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney.
Sequence Similarities: Belongs to the semaphorin family.
Cellular Location: Cell membrane.

Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.
Database Links:
  • Entrez Gene: 8482?Human
  • Entrez Gene: 20361?Mouse
  • Omim: 607961?Human
  • SwissProt: O75326?Human
  • SwissProt: Q9QUR8?Mouse
  • Unigene: 24640?Human
  • Unigene: 335187?Mouse
    		•
    Synonyms:
  • CD 108 Antibody
  • CD108 Antibody
  • CD108 antigen Antibody
  • CDw108 Antibody
  • H Sema K1 Antibody
  • H Sema L Antibody
  • H-SEMA-K1 Antibody
  • H-Sema-L Antibody
  • JMH Antibody
  • JMH blood group antigen Antibody
  • John Milton Hagen blood group H Sema K1 Antibody
  • John Milton Hargen human blood group Ag Antibody
  • John-Milton-Hargen human blood group Ag Antibody
  • MGC126692 Antibody
  • MGC126696 Antibody
  • SEM7A_HUMAN Antibody
  • Sema domain immunoglobulin domain (Ig) and GPI membrane anchor 7A Antibody
  • Sema K1 Antibody
  • Sema L Antibody
  • SEMA7A Antibody
  • SEMAK1 Antibody
  • SEMAL Antibody
  • Semaphorin 7a Antibody
  • Semaphorin 7A GPI membrane anchor Antibody
  • Semaphorin K1 Antibody
  • Semaphorin L Antibody
  • Semaphorin-7A Antibody
  • Semaphorin-K1 Antibody
  • Semaphorin-L Antibody
  • Semaphorin7a Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号