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Anti-SEMA4C Antibody

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产品名称: Anti-SEMA4C Antibody
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简单介绍

Anti-SEMA4C Antibody


Anti-SEMA4C Antibody  的详细介绍
Name: Anti-SEMA4C Antibody
See all SEMA4C primary antibodies
Description: Rabbit polyclonal antibody to SEMA4C
Specificity: The antibody detects endogenous levels of total SEMA4C protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.1mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Sequence Similarities: Belongs to the semaphorin family.
Cellular Location: Cell junction > Synapse > Postsynaptic cell membrane > Postsynaptic density. Cytoplasmic vesicle > Secretory vesicle > Synaptic vesicle membrane.
Database Links:
  • Entrez Gene: 54910?Human
  • Omim: 604462?Human
  • SwissProt: Q9C0C4?Human
  • Unigene: 516220?Human
    		•
    Synonyms:
  • KIAA1739 Antibody
  • M-SEMA-F Antibody
  • S4c Antibody
  • SEM4C_HUMAN Antibody
  • Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Antibody
  • SEMA4C Antibody
  • SEMACL1 Antibody
  • SEMAF Antibody
  • SEMAI Antibody
  • Semaphorin-4C Antibody
  • UNQ5855/PRO34487 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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