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Anti-SELPLG Antibody

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产品名称: Anti-SELPLG Antibody
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Anti-SELPLG Antibody


Anti-SELPLG Antibody  的详细介绍
Name: Anti-SELPLG Antibody
See all SELPLG primary antibodies
Description: Rabbit polyclonal antibody to SELPLG.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
Reactivity: Human
Immunogen: Recombinant protein of human SELPLG.
Protein Length: 412
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.
Tissue Specificity: Expressed on neutrophils, monocytes and most lymphocytes.
Post-Translational Modification: Displays complex, core-2, sialylated and fucosylated O-linked oligosaccharides, at least some of which appear to contain poly-N-acetyllactosamine with varying degrees of substitution. Mainly disialylated or neutral forms of the core-2 tetrasaccharide, Galbeta1-->4GlcNAcbeta1-->6(Galbeta1-->3)GalNAcOH. The GlcN:GalN ratio is approximately 2:1 and the Man:Fuc ratio 3:5. Contains about 14% fucose with alpha-1,3 linkage present in two forms: One species is a disialylated, monofucosylated glycan, and the other, a monosialylated, trifucosylated glycan with a polylactosamine backbone. The fucosylated forms carry the Lewis antigen and are important for interaction with selectins and for functioning in leukocyte rolling. The modification containing the sialyl Lewis X glycan is on Thr-57. No sulfated O-glycans. Some N-glycosylation.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 6404?Human
  • Omim: 600738?Human
  • SwissProt: Q14242?Human
  • Unigene: 591014?Human
    		•
    Synonyms:
  • CD 162 Antibody
  • CD162 Antibody
  • CD162 antigen Antibody
  • CLA Antibody
  • Cutaneous lymphocyte associated associated antigen Antibody
  • P selectin glycoprotein ligand 1 Antibody
  • P selectin glycoprotein ligand 1 precursor Antibody
  • P-selectin glycoprotein ligand 1 Antibody
  • PSGL 1 Antibody
  • PSGL-1 Antibody
  • PSGL1 Antibody
  • Selectin P ligand Antibody
  • SELPLG Antibody
  • SELPL_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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