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Anti-SDCCAG8 Antibody

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产品名称: Anti-SDCCAG8 Antibody
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简单介绍

Anti-SDCCAG8 Antibody


Anti-SDCCAG8 Antibody  的详细介绍
Name: Anti-SDCCAG8 Antibody
See all SDCCAG8 primary antibodies
Description: Goat polyclonal antibody to SDCCAG8.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human SDCCAG8 (internal region).
Sequence: C-TINDQSQYIHHLEAE
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.
Tissue Specificity: Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
Involvement in Disease: Senior-Loken syndrome 7: A renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life.

Bardet-Biedl syndrome 16: A syndrome characterized by usually severe pigmentary retinopathy, early-onset obesity, polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus, hypertension and congenital heart disease. Bardet-Biedl syndrome inheritance is autosomal recessive, but three mutated alleles (two at one locus, and a third at a second locus) may be required for clinical manifestation of some forms of the disease.
Cellular Location: Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome > Centriole. Cell junction.

Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.
Database Links:
  • Entrez Gene: 10806 Human
  • Omim: 613524 Human
  • SwissProt: Q86SQ7 Human
  • Unigene: 591530 Human
    		•
    Synonyms:
  • Antigen NY CO 8 Antibody
  • Antigen NY-CO-8 Antibody
  • BBS16 Antibody
  • CCCAP Antibody
  • CCCAP SLSN7 Antibody
  • Centrosomal colon cancer autoantigen protein Antibody
  • hCCCAP Antibody
  • HSPC085 Antibody
  • NPHP10 Antibody
  • NPHP10 gene Antibody
  • NY-CO-8 Antibody
  • SDCCAG8 Antibody
  • SDCG8_HUMAN Antibody
  • Serologically defined colon cancer antigen 8 Antibody
  • Serologically defined colon cancer antigen 8 homolog Antibody
  • SLSN7 Antibody
  • SLSN7 gene Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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