产品资料

Anti-RGS10 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-RGS10 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-RGS10 Antibody


Anti-RGS10 Antibody  的详细介绍
Name: Anti-RGS10 Antibody
See all RGS10 primary antibodies
Description: Rabbit polyclonal antibody to RGS10
Specificity: RGS10 pAb detects endogenous levels of RGS10 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 357-402 of Human RGS10.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 20 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:8774883, PubMed:10608901, PubMed:9353196, PubMed:11443111, PubMed:18434541). Modulates the activity of potassium channels that are activated in response to CHRM2 signaling (PubMed:11443111). Activity on GNAZ is inhibited by palmitoylation of the G-protein (PubMed:9353196).
Post-Translational Modification: Isoform 3 is phosphorylated on Ser-16.
Cellular Location: Cytoplasm > Cytosol. Nucleus.

Forskolin treatment promotes phosphorylation and translocation to the nucleus.
Database Links:
  • Entrez Gene: 6001?Human
  • Entrez Gene: 67865?Mouse
  • Entrez Gene: 54290?Rat
  • Omim: 602856?Human
  • SwissProt: O43665?Human
  • SwissProt: Q9CQE5?Mouse
  • SwissProt: P49806?Rat
  • Unigene: 501200?Human
  • Unigene: 18635?Mouse
  • Unigene: 23957?Rat
    		•
    Synonyms:
  • Regulator of G protein signaling 10 Antibody
  • Regulator of G-protein signaling 10 Antibody
  • RGS10 Antibody
  • RGS10_HUMAN Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号