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Antibodies
Anti-RBBP4 Antibody
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产品名称:
Anti-RBBP4 Antibody
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简单介绍
Anti-RBBP4
Antibody
Anti-RBBP4 Antibody
的详细介绍
Overview
Name:
Anti-RBBP4
Antibody
See all RBBP4 primary antibodies
Description:
Rabbit polyclonal antibody to RBBP4
Specificity:
RBBP4 pAb detects endogenous levels of RBBP4 protein.
Applications:
WB, IHC, IF, IP, CHIP
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant full length Human RBBP4.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Molecular Weight:
~ 48 kDa
Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:
1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Target
Function:
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
Sequence Similarities:
Belongs to the WD repeat RBAP46/RBAP48/MSI1 family.
Cellular Location:
Nucleus.
Database Links:
Entrez Gene: 5928?Human
Entrez Gene: 19646?Mouse
Entrez Gene: 313048?Rat
Omim: 602923?Human
SwissProt: Q09028?Human
SwissProt: Q60972?Mouse
Unigene: 16003?Human
Unigene: 12145?Mouse
Synonyms:
CAF I p48 Antibody
CAF-1 subunit C Antibody
CAF-I 48 kDa subunit Antibody
CAF-I p48 Antibody
Chromatin assembly factor 1 subunit C Antibody
Chromatin assembly factor I p48 subunit Antibody
Chromatin assembly factor/CAF 1 p48 subunit Antibody
Histone-binding protein RBBP4 Antibody
MSI1 protein homolog Antibody
Nucleosome-remodeling factor subunit RBAP48 Antibody
NURF55 Antibody
RB binding protein 4 chromatin remodeling factor Antibody
RbAp 48 Antibody
RbAp48 Antibody
RBBP-4 Antibody
RBBP4 Antibody
RBBP4_HUMAN Antibody
Retinoblastoma binding protein 4 Antibody
Retinoblastoma binding protein p48 Antibody
Retinoblastoma-binding protein 4 Antibody
Retinoblastoma-binding protein p48 Antibody
Information:
Target information shown above is from the UniProt Consortium.
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