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Anti-RASSF7 Antibody

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产品名称: Anti-RASSF7 Antibody
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简单介绍

Anti-RASSF7 Antibody


Anti-RASSF7 Antibody  的详细介绍
Name: Anti-RASSF7 Antibody
See all RASSF7 primary antibodies
Description: Rabbit polyclonal antibody to RASSF7
Specificity: The antibody detects endogenous levels of total RASSF7 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human Ras association (RalGDS / AF-6) domain family (N-terminal) member 7
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.6mg / ml
Formulation: Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Storage: Store at -20?C
Function: Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization.
Post-Translational Modification: Polyubiquitinated and degraded by the proteasome upon prolonged stress stimuli.
Cellular Location: Cytoplasm > Cytoskeleton > Microtubule organizing center > Centrosome.

Colocalizes with gamma-tubulin.
Database Links:
  • Entrez Gene: 8045?Human
  • Omim: 143023?Human
  • SwissProt: Q02833?Human
  • Unigene: 72925?Human
    		•
    Synonyms:
  • C11orf13 Antibody
  • Chromosome 11 open reading frame 13 Antibody
  • HRAS1 Antibody
  • HRAS1 related cluster 1 Antibody
  • HRAS1 related cluster protein 1 Antibody
  • HRAS1-related cluster protein 1 Antibody
  • HRC1 Antibody
  • MGC126069 Antibody
  • MGC126070 Antibody
  • Ras association (RalGDS/AF 6) domain family (N terminal) member 7 Antibody
  • Ras association (RalGDS/AF 6) domain family 7 Antibody
  • Ras association domain containing protein 7 Antibody
  • Ras association domain-containing protein 7 Antibody
  • RASF7_HUMAN Antibody
  • RASSF 7 Antibody
  • RASSF7 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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