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Anti-RanBP9 Antibody

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产品名称: Anti-RanBP9 Antibody
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Anti-RanBP9 Antibody


Anti-RanBP9 Antibody  的详细介绍
Name: Anti-RanBP9 Antibody
See all RanBP9 primary antibodies
Description: Mouse IgG1 monoclonal antibody to RanBP9
Specificity: This antibody detects endogenous levels of RanBP9 and does not cross-react with related proteins
Applications: WB, IP, ICC
Reactivity: Human
Immunogen: Recombinant full length Human RanBP9.
Host: Mouse IgG1
Clonality: Monoclonal
Conjugate: Unconjugated
Molecular Weight: Predicted band size:78KDa Observed band size:95KDa
Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Function: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity).
Tissue Specificity: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.
Sequence Similarities: Belongs to the RANBP9/10 family.
Post-Translational Modification: Phosphorylated in response to stress. Can be phosphorylated by the cleaved p110 form of CDC2L1 (p110C).
Cellular Location: Cytoplasm. Nucleus. Cell membrane.

The unphosphorylated form is predominantly cytoplasmic. A phosphorylated form is associated with the plasma membrane.
Database Links:
  • Entrez Gene: 10048 Human
  • Omim: 603854 Human
  • SwissProt: Q96S59 Human
  • Unigene: 708182 Human
    		•
    Synonyms:
  • B cell antigen receptor Ig beta associated protein 1 Antibody
  • BPM 90 Antibody
  • BPM L Antibody
  • BPM-L Antibody
  • BPM90 Antibody
  • BPML Antibody
  • IBAP 1 Antibody
  • Imp 9 Antibody
  • Importin 9 Antibody
  • Novel centrosomal protein RanBPM Antibody
  • RAN binding protein 9 Antibody
  • Ran binding protein centrosomal Antibody
  • Ran Binding Protein in the Microtubule organizing center Antibody
  • Ran binding protein M Antibody
  • Ran BP9 Antibody
  • Ran-binding protein 9 Antibody
  • Ran-binding protein M Antibody
  • RANB9_HUMAN Antibody
  • RanBP 7 Antibody
  • RANBP 9 Antibody
  • RanBP7 Antibody
  • RanBP9 Antibody
  • RanBPM Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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