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Anti-ATF3 (N159) Antibody

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产品名称: Anti-ATF3 (N159) Antibody
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Anti-ATF3 (N159) Antibody


Anti-ATF3 (N159) Antibody  的详细介绍
Name: Anti-ATF3 (N159) Antibody
See all ATF3 primary antibodies
Description: Rabbit polyclonal antibody to ATF3 (N159)
Specificity: ATF-3 (N159) pAb detects endogenous levels of ATF-3 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 120-170 of Human ATF3.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 21 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Sequence Similarities: Belongs to the bZIP family. ATF subfamily.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 467?Human
  • Entrez Gene: 11910?Mouse
  • Entrez Gene: 25389?Rat
  • Omim: 603148?Human
  • SwissProt: P18847?Human
  • SwissProt: Q60765?Mouse
  • SwissProt: P29596?Rat
  • Unigene: 460?Human
  • Unigene: 2706?Mouse
  • Unigene: 9664?Rat
    		•
    Synonyms:
  • Activating transcription factor 3 Antibody
  • ATF3 Antibody
  • ATF3deltaZip2 Antibody
  • ATF3deltaZip2c Antibody
  • ATF3deltaZip3 Antibody
  • ATF3_HUMAN Antibody
  • cAMP dependent transcription factor ATF3 Antibody
  • cAMP-dependent transcription factor ATF-3 Antibody
  • Cyclic AMP dependent transcription factor ATF3 Antibody
  • Cyclic AMP-dependent transcription factor ATF-3 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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