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Anti-ASCL1 (E158) Antibody

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产品名称: Anti-ASCL1 (E158) Antibody
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Anti-ASCL1 (E158) Antibody


Anti-ASCL1 (E158) Antibody  的详细介绍
Name: Anti-ASCL1 (E158) Antibody
See all ASCL1 primary antibodies
Description: Rabbit polyclonal antibody to ASCL1 (E158)
Specificity: ASCL1 (E158) pAb detects endogenous levels of ASCL1 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 140-190 of Human ASCL1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 25 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 429?Human
  • Entrez Gene: 17172?Mouse
  • Entrez Gene: 64186?Rat
  • Omim: 100790?Human
  • SwissProt: P50553?Human
  • SwissProt: Q02067?Mouse
  • SwissProt: P19359?Rat
  • Unigene: 703025?Human
  • Unigene: 136217?Mouse
  • Unigene: 32936?Rat
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    Synonyms:
  • Achaete scute complex homolog 1 Antibody
  • Achaete scute complex homolog like 1 Antibody
  • Achaete scute complex homologue 1 Antibody
  • Achaete scute complex homologue like 1 Antibody
  • Achaete scute complex like 1 Antibody
  • Achaete scute family bHLH transcription factor 1 Antibody
  • Achaete scute protein Antibody
  • Achaete-scute homolog 1 Antibody
  • Ascl 1 Antibody
  • ascl1 Antibody
  • ASCL1_HUMAN Antibody
  • Ash 1 Antibody
  • ASH-1 Antibody
  • Ash1 Antibody
  • bHLHa46 Antibody
  • Class A basic helix-loop-helix protein 46 Antibody
  • Hash 1 Antibody
  • HASH1 Antibody
  • Mammalian achaete scute homolog 1 Antibody
  • Mammalian achaete scute homologue 1 Antibody
  • Mash 1 Antibody
  • Mash1 Antibody
  • MASH1/Achaete-scute homolog 1 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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