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Anti-AKR1A1 Antibody

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产品名称: Anti-AKR1A1 Antibody
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简单介绍

Anti-AKR1A1 Antibody


Anti-AKR1A1 Antibody  的详细介绍
Name: Anti-AKR1A1 Antibody
See all AKR1A1 primary antibodies
Description: Goat polyclonal antibody to AKR1A1.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human AKR1A1 (C terminal).
Sequence: C-DAGHPLYPFNDPY
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).
Tissue Specificity: Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung.
Sequence Similarities: Belongs to the aldo/keto reductase family.
Database Links:
  • Entrez Gene: 10327 Human
  • Omim: 103830 Human
  • SwissProt: P14550 Human
  • Unigene: 474584 Human
    		•
    Synonyms:
  • AK1A1_HUMAN Antibody
  • AKR1A1 Antibody
  • Alcohol dehydrogenase Antibody
  • Alcohol dehydrogenase [NADP+] Antibody
  • Aldehyde reductase Antibody
  • Aldo keto reductase family 1 member A1 (aldehyde reductase) Antibody
  • Aldo-keto reductase family 1 member A1 Antibody
  • ALDR1 Antibody
  • ALR Antibody
  • ARM Antibody
  • DD3 Antibody
  • MGC12529 Antibody
  • MGC1380 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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